Most diagnostic studies (including type and screen) obtained from the bone marrow are accurate. However, there may be inaccuracies for WBC count, oxygenation, potassium, AST, ALT and ionized calcium. Once, medications are infused into the bone marrow, subsequent laboratory tests may be inaccurate.
IO lines should be viewed as temporary and venous access should be obtained as soon as possible and the IO removed. IOs in place longer than 24 hours have been associated with osteomyelitis. Fractures have been associated with IO placement as has compartment syndrome from infiltration. Fat and bone marrow emboli can occur with IO placement, but their consequence is poorly understood. Despite these risk, IO placement is very safe with complications occurring in less than 1 percent of patients.
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